A Statistical Approach for Rare-Variant Association Testing in Affected Sibships

Sequencing and exome-chip technologies have motivated development of novel statistical tests to identify rare genetic variation that influences complex diseases. Although many rare-variant association tests exist for case-control or cross-sectional studies, far fewer methods exist for testing associ...

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Publicado no:Am J Hum Genet
Main Authors: Epstein, Michael P., Duncan, Richard, Ware, Erin B., Jhun, Min A., Bielak, Lawrence F., Zhao, Wei, Smith, Jennifer A., Peyser, Patricia A., Kardia, Sharon L.R., Satten, Glen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385187/
https://ncbi.nlm.nih.gov/pubmed/25799106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.01.020
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