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A Statistical Approach for Rare-Variant Association Testing in Affected Sibships
Sequencing and exome-chip technologies have motivated development of novel statistical tests to identify rare genetic variation that influences complex diseases. Although many rare-variant association tests exist for case-control or cross-sectional studies, far fewer methods exist for testing associ...
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| Veröffentlicht in: | Am J Hum Genet |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385187/ https://ncbi.nlm.nih.gov/pubmed/25799106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.01.020 |
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