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Patency of Litomosoides sigmodontis infection depends on Toll‐like receptor 4 whereas Toll‐like receptor 2 signalling influences filarial‐specific CD4(+) T‐cell responses

BALB/c mice develop a patent state [release of microfilariae (Mf), the transmission life‐stage, into the periphery] when exposed to the rodent filariae Litomosoides sigmodontis. Interestingly, only a portion of the infected mice become patent, which reflects the situation in human individuals infect...

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Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Rodrigo, Maria B., Schulz, Sandy, Krupp, Vanessa, Ritter, Manuel, Wiszniewsky, Katharina, Arndts, Kathrin, Tamadaho, Ruth S. E., Endl, Elmar, Hoerauf, Achim, Layland, Laura E.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799886/
https://ncbi.nlm.nih.gov/pubmed/26714796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12573
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