Acid Ceramidase Treatment Enhances the Outcome of Autologous Chondrocyte Implantation in a Rat Osteochondral Defect Model

OBJECTIVE: The overall aim of this study was to evaluate how supplementation of chondrocyte media with recombinant acid ceramidase (rhAC) influenced cartilage repair in a rat osteochondral defect model. METHODS: Primary chondrocytes were grown as monolayers in polystyrene culture dishes with and wit...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Frohbergh, Michael E., Guevara, Johana M., Grelsamer, Ronald P., Barbe, Mary F., He, Xingxuan, Simonaro, Calogera M., Schuchman, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799741/
https://ncbi.nlm.nih.gov/pubmed/26524412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.10.016
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