Cathepsin D: an Mϕ-derived factor mediating increased endothelial cell permeability with implications for alteration of the blood-retinal barrier in diabetic retinopathy

Inflammation plays an important role in the pathogenesis of diabetic retinopathy (DR). We have previously reported increased monocyte (Mono) trafficking into the retinas of diabetic animals. In this study, we have examined the effect of activated Monos on retinal endothelial cells (ECs). The U937 Mϕ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Monickaraj, Finny, McGuire, Paul G., Nitta, Carolina Franco, Ghosh, Kaustabh, Das, Arup
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2016
Teme:
Research Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799507/
https://ncbi.nlm.nih.gov/pubmed/26718887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-279802
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