Cathepsin D: an Mϕ-derived factor mediating increased endothelial cell permeability with implications for alteration of the blood-retinal barrier in diabetic retinopathy

Inflammation plays an important role in the pathogenesis of diabetic retinopathy (DR). We have previously reported increased monocyte (Mono) trafficking into the retinas of diabetic animals. In this study, we have examined the effect of activated Monos on retinal endothelial cells (ECs). The U937 Mϕ...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Monickaraj, Finny, McGuire, Paul G., Nitta, Carolina Franco, Ghosh, Kaustabh, Das, Arup
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4799507/
https://ncbi.nlm.nih.gov/pubmed/26718887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-279802
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