Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells

Pluripotency transcription programs by core transcription factors (CTFs) might be reset during M/G1 transition to maintain the pluripotency of embryonic stem cells (ESCs). However, little is known about how CTFs are governed during cell cycle progression. Here, we demonstrate that the regulation of...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Shin, Jihoon, Kim, Tae Wan, Kim, Hyunsoo, Kim, Hye Ji, Suh, Min Young, Lee, Sangho, Lee, Han-Teo, Kwak, Sojung, Lee, Sang-Eun, Lee, Jong-Hyuk, Jang, Hyonchol, Cho, Eun-Jung, Youn, Hong-Duk
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798952/
https://ncbi.nlm.nih.gov/pubmed/26880562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10877
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