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Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation
Genetic alterations which impair the function of the TP53 signaling pathway in TP53 wild-type human tumors remain elusive. To identify new components of this pathway, we performed a screen for genes whose loss-of-function debilitated TP53 signaling and enabled oncogenic transformation of human mamma...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4798945/ https://ncbi.nlm.nih.gov/pubmed/26956429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07101 |
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