Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis

Emergency myelopoiesis is inflammation-induced hematopoiesis to replenish myeloid cells in the periphery, which is critical to control the infection with pathogens. Previously, pro-inflammatory cytokines such as interferon (IFN)-α and IFN-γ were demonstrated to play a critical role in the expansion...

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Vydáno v:PLoS Pathog
Hlavní autoři: Furusawa, Jun-ichi, Mizoguchi, Izuru, Chiba, Yukino, Hisada, Masayuki, Kobayashi, Fumie, Yoshida, Hiroki, Nakae, Susumu, Tsuchida, Akihiko, Matsumoto, Tetsuya, Ema, Hideo, Mizuguchi, Junichiro, Yoshimoto, Takayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4798290/
https://ncbi.nlm.nih.gov/pubmed/26991425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005507
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