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Abrogation of age-induced microRNA-195 rejuvenates the senescent mesenchymal stem cells by reactivating telomerase

Previously, we reported that a novel sub-population of young mesenchymal stem cells (YMSCs) existed in old bone marrow, which possessed high anti-aging properties as well as excellent efficacy for cardiac repair. MicroRNAs (miRNAs) have emerged as key regulators in post-transcriptional gene expressi...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Okada, Motoi, Kim, Ha Won, Matsu-ura, Kaoru, Wang, Yi-Gang, Xu, Meifeng, Ashraf, Muhammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797648/
https://ncbi.nlm.nih.gov/pubmed/26390028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2211
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