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Prolonged drug delivery system of an antifungal drug by association with polyamidoamine dendrimers

INTRODUCTION: The potent antifungal agent amphotericin B (AmB) is not freely soluble in water. The clinical use of AmB is limited by nephrotoxicity and poor water solubility. Polyamidoamine (PAMAM) dendrimer offers an identical carrier for drug binding that has the capacity to attach and discharge d...

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書目詳細資料
發表在:Int J Pharm Investig
Main Authors: Jose, Jobin, Charyulu, R Narayana
格式: Artigo
語言:Inglês
出版: Medknow Publications & Media Pvt Ltd 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797489/
https://ncbi.nlm.nih.gov/pubmed/27051632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.177833
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