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Prolonged drug delivery system of an antifungal drug by association with polyamidoamine dendrimers

INTRODUCTION: The potent antifungal agent amphotericin B (AmB) is not freely soluble in water. The clinical use of AmB is limited by nephrotoxicity and poor water solubility. Polyamidoamine (PAMAM) dendrimer offers an identical carrier for drug binding that has the capacity to attach and discharge d...

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Publicado en:Int J Pharm Investig
Autores principales: Jose, Jobin, Charyulu, R Narayana
Formato: Artigo
Lenguaje:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797489/
https://ncbi.nlm.nih.gov/pubmed/27051632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.177833
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