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Prolonged drug delivery system of an antifungal drug by association with polyamidoamine dendrimers

INTRODUCTION: The potent antifungal agent amphotericin B (AmB) is not freely soluble in water. The clinical use of AmB is limited by nephrotoxicity and poor water solubility. Polyamidoamine (PAMAM) dendrimer offers an identical carrier for drug binding that has the capacity to attach and discharge d...

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Detalhes bibliográficos
Publicado no:Int J Pharm Investig
Main Authors: Jose, Jobin, Charyulu, R Narayana
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797489/
https://ncbi.nlm.nih.gov/pubmed/27051632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.177833
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