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Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition

With bacterial resistance becoming a serious threat to global public health, antimicrobial peptides (AMPs) have become a promising area of focus in antibiotic research. AMPs are derived from a diverse range of species, from prokaryotes to humans, with a mechanism of action that often involves disrup...

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Publicado en:Nucleic Acids Res
Autores principales: Gagnon, Matthieu G., Roy, Raktim N., Lomakin, Ivan B., Florin, Tanja, Mankin, Alexander S., Steitz, Thomas A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797290/
https://ncbi.nlm.nih.gov/pubmed/26809677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw018
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