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Structural Basis for the Rescue of Stalled Ribosomes: Structure of YaeJ Bound to the Ribosome

In bacteria, the hybrid transfer-messenger RNA (tmRNA) rescues ribosomes stalled on defective messenger RNAs (mRNAs). However, certain gram-negative bacteria have evolved proteins that are capable of rescuing stalled ribosomes in a tmRNA-independent manner. Here, we report a 3.2 angstrom–resolution...

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Bibliographic Details
Main Authors: Gagnon, Matthieu G., Seetharaman, Sai V., Bulkley, David, Steitz, Thomas A.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377438/
https://ncbi.nlm.nih.gov/pubmed/22422986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1217443
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