Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and Chorioallantoic Fusion

EDD is the mammalian ortholog of the Drosophila melanogaster hyperplastic disc gene (hyd), which is critical for cell proliferation and differentiation in flies through regulation of hedgehog and decapentaplegic signaling. Amplification and overexpression of EDD occurs frequently in several cancers,...

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Autores principales: Saunders, Darren N., Hird, Samantha L., Withington, Sarah L., Dunwoodie, Sally L., Henderson, Michelle J., Biben, Christine, Sutherland, Robert L., Ormandy, Christopher J., Watts, Colin K. W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC479729/
https://ncbi.nlm.nih.gov/pubmed/15282321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7225-7234.2004
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