Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and Chorioallantoic Fusion

EDD is the mammalian ortholog of the Drosophila melanogaster hyperplastic disc gene (hyd), which is critical for cell proliferation and differentiation in flies through regulation of hedgehog and decapentaplegic signaling. Amplification and overexpression of EDD occurs frequently in several cancers,...

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Detalhes bibliográficos
Main Authors: Saunders, Darren N., Hird, Samantha L., Withington, Sarah L., Dunwoodie, Sally L., Henderson, Michelle J., Biben, Christine, Sutherland, Robert L., Ormandy, Christopher J., Watts, Colin K. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC479729/
https://ncbi.nlm.nih.gov/pubmed/15282321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7225-7234.2004
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