Edd, the Murine Hyperplastic Disc Gene, Is Essential for Yolk Sac Vascularization and Chorioallantoic Fusion

EDD is the mammalian ortholog of the Drosophila melanogaster hyperplastic disc gene (hyd), which is critical for cell proliferation and differentiation in flies through regulation of hedgehog and decapentaplegic signaling. Amplification and overexpression of EDD occurs frequently in several cancers,...

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Main Authors: Saunders, Darren N., Hird, Samantha L., Withington, Sarah L., Dunwoodie, Sally L., Henderson, Michelle J., Biben, Christine, Sutherland, Robert L., Ormandy, Christopher J., Watts, Colin K. W.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2004
主題:
Mammalian Genetic Models with Minimal or Complex Phenotypes
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC479729/
https://ncbi.nlm.nih.gov/pubmed/15282321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7225-7234.2004
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