Budding Yeast Silencing Complexes and Regulation of Sir2 Activity by Protein-Protein Interactions
Gene silencing in the budding yeast Saccharomyces cerevisiae requires the enzymatic activity of the Sir2 protein, a highly conserved NAD-dependent deacetylase. In order to study the activity of native Sir2, we purified and characterized two budding yeast Sir2 complexes: the Sir2/Sir4 complex, which...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC479720/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.16.6931-6946.2004 |
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