Circular RNA enrichment in platelets is a signature of transcriptome degradation

In platelets, splicing and translation occur in the absence of a nucleus. However, the integrity and stability of mRNAs derived from megakaryocyte progenitor cells remain poorly quantified on a transcriptome-wide level. As circular RNAs (circRNAs) are resistant to degradation by exonucleases, their...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Alhasan, Abd A., Izuogu, Osagie G., Al-Balool, Haya H., Steyn, Jannetta S., Evans, Amanda, Colzani, Maria, Ghevaert, Cedric, Mountford, Joanne C., Marenah, Lamin, Elliott, David J., Santibanez-Koref, Mauro, Jackson, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797142/
https://ncbi.nlm.nih.gov/pubmed/26660425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-649434
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