Estrogens and Progesterone Promote Persistent CCND1 Gene Activation during G(1) by Inducing Transcriptional Derepression via c-Jun/c-Fos/Estrogen Receptor (Progesterone Receptor) Complex Assembly to a Distal Regulatory Element and Recruitment of Cyclin D1 to Its Own Gene Promoter

Transcriptional activation of the cyclin D1 gene (CCND1) plays a pivotal role in G(1)-phase progression, which is thereby controlled by multiple regulatory factors, including nuclear receptors (NRs). Appropriate CCND1 gene activity is essential for normal development and physiology of the mammary gl...

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Bibliographic Details
Main Authors: Cicatiello, Luigi, Addeo, Raffaele, Sasso, Annarita, Altucci, Lucia, Petrizzi, Valeria Belsito, Borgo, Raphaelle, Cancemi, Massimo, Caporali, Simona, Caristi, Silvana, Scafoglio, Claudio, Teti, Diana, Bresciani, Francesco, Perillo, Bruno, Weisz, Alessandro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC479712/
https://ncbi.nlm.nih.gov/pubmed/15282324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.16.7260-7274.2004
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