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Sox2 in the differentiation of cochlear progenitor cells

HMG domain transcription factor, Sox2, is a critical gene for the development of cochlear hair cells, the receptor cells for hearing, but this has been ascribed to expansion of the progenitors that become hair cells. Here, we show that Sox2 activated Atoh1, a transcription factor important for hair...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kempfle, Judith S., Turban, Jack L., Edge, Albert S. B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796895/
https://ncbi.nlm.nih.gov/pubmed/26988140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23293
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