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Sox2 in the differentiation of cochlear progenitor cells

HMG domain transcription factor, Sox2, is a critical gene for the development of cochlear hair cells, the receptor cells for hearing, but this has been ascribed to expansion of the progenitors that become hair cells. Here, we show that Sox2 activated Atoh1, a transcription factor important for hair...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Kempfle, Judith S., Turban, Jack L., Edge, Albert S. B.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796895/
https://ncbi.nlm.nih.gov/pubmed/26988140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23293
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