Genetic Association of Curative and Adverse Reactions to Tyrosine Kinase Inhibitors in Chinese advanced Non-Small Cell Lung Cancer patients

Epidermal growth factor receptor (EGFR) Tyrosine kinase inhibitor (TKI) is an effective targeted therapy for advanced non-small cell lung cancer (NSCLC) but also causes adverse drug reactions (ADRs) e.g., skin rash and diarrhea. SNPs in the EGFR signal pathway, drug metabolism/ transport pathways an...

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Publicat a:Sci Rep
Autors principals: Ruan, Yunfeng, Jiang, Jie, Guo, Liang, Li, Yan, Huang, Hailiang, Shen, Lu, Luan, Mengqi, Li, Mo, Du, Huihui, Ma, Cheng, He, Lin, Zhang, Xiaoqing, Qin, Shengying
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796893/
https://ncbi.nlm.nih.gov/pubmed/26988277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23368
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