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Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

An increasing number of women fail to achieve pregnancy due to either failed fertilization or embryo arrest during preimplantation development. This often results from decreased oocyte quality. Indeed, reduced mitochondrial DNA copy number (mitochondrial DNA deficiency) may disrupt oocyte quality in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cagnone, Gael L. M., Tsai, Te-Sha, Makanji, Yogeshwar, Matthews, Pamela, Gould, Jodee, Bonkowski, Michael S., Elgass, Kirstin D., Wong, Ashley S. A., Wu, Lindsay E., McKenzie, Matthew, Sinclair, David A., John, Justin C. St.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796791/
https://ncbi.nlm.nih.gov/pubmed/26987907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23229
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