Accelerated cardiac remodeling in desmoplakin transgenic mice in response to endurance exercise is associated with perturbed Wnt/β-catenin signaling

Arrhythmogenic ventricular cardiomyopathy (AVC) is a frequent underlying cause for arrhythmias and sudden cardiac death especially during intense exercise. The mechanisms involved remain largely unknown. The purpose of this study was to investigate how chronic endurance exercise contributes to desmo...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Martherus, Ruben, Jain, Rahul, Takagi, Ken, Mendsaikhan, Uzmee, Turdi, Subat, Osinska, Hanna, James, Jeanne F., Kramer, Kristen, Purevjav, Enkhsaikhan, Towbin, Jeffrey A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796627/
https://ncbi.nlm.nih.gov/pubmed/26545710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00295.2015
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