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Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice
Immune tolerance is executed partly by Foxp3(+)regulatory T (Treg) cells, which suppress autoreactive T cells. In autoimmune type 1 diabetes (T1D) impaired tolerance promotes destruction of insulin-producing β-cells. The development of autoantigen-specific vaccination strategies for Foxp3(+)Treg-ind...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4796321/ https://ncbi.nlm.nih.gov/pubmed/26975663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10991 |
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