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Role of Smad3 in platelet-derived growth factor-C-induced liver fibrosis

Chronic liver injury leads to fibrosis and cirrhosis. Cirrhosis, the end stage of chronic liver disease, is a leading cause of death worldwide and increases the risk of developing hepatocellular carcinoma. Currently, there is a lack of effective antifibrotic therapies to treat fibrosis and cirrhosis...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Lee, Jung Il, Wright, Jocelyn H., Johnson, Melissa M., Bauer, Renay L., Sorg, Kristina, Yuen, Sebastian, Hayes, Brian J., Nguyen, Lananh, Riehle, Kimberly J., Campbell, Jean S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796282/
https://ncbi.nlm.nih.gov/pubmed/26632601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00423.2014
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