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Rapamycin Inhibits Cardiac Hypertrophy by Promoting Autophagy via the MEK/ERK/Beclin-1 Pathway

Rapamycin, also known as sirolimus, is an antifungal agent and immunosuppressant drug used to prevent organ rejection in transplantation. However, little is known about the role of rapamycin in cardiac hypertrophy and the signaling pathways involved. Here, the effect of rapamycin was examined using...

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Bibliografiska uppgifter
I publikationen:Front Physiol
Huvudupphovsmän: Gu, Jun, Hu, Wei, Song, Zhi-Ping, Chen, Yue-Guang, Zhang, Da-Dong, Wang, Chang-Qian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796007/
https://ncbi.nlm.nih.gov/pubmed/27047390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00104
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