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α-Arylation/Heteroarylation of Chiral α-Aminomethyltrifluoroborates via Synergistic Iridium Photoredox/Nickel Cross-Coupling Catalysis

Direct access to complex, enantiopure benzylamine architectures using a synergistic iridium photoredox/nickel cross-coupling dual catalysis strategy has been developed, where Csp(3)-Csp(2) bonds are forged, starting from abundant and inexpensive natural amino acids.

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: El Khatib, Mirna, Serafim, Ricardo Augusto Massarico, Molander, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795823/
https://ncbi.nlm.nih.gov/pubmed/26592731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506147
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