Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G

Protease-mediated degradation of proteins is critical in a plethora of physiological processes. Neutrophils secrete serine proteases including cathepsin G (CatG), neutrophile elastase (NE), and proteinase 3 (PR3) together with lactoferrin (LF) as a first cellular immune response against pathogens. H...

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Publicado en:PLoS One
Autores principales: Eipper, Steffen, Steiner, Robin, Lesner, Adam, Sienczyk, Marcin, Palesch, David, Halatsch, Marc-Eric, Zaczynska, Ewa, Heim, Christopher, Hartmann, Marcus D., Zimecki, Michal, Wirtz, Christian Rainer, Burster, Timo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795699/
https://ncbi.nlm.nih.gov/pubmed/26986619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151509
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