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Highly Diastereoselective Michael Reactions Using β-Nitrocarbonyl Nucleophiles

We have discovered a highly diastereoselective Michael reaction of α-substituted, β-nitrocarbonyl compounds to deliver highly functionalized stereo-diads containing fully substituted nitrogen-bearing centers. Good to excellent yields and diastereoselectivities are observed. This transformation is to...

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Vydáno v:Org Lett
Hlavní autoři: Gietter-Burch, Amber A. S., Mitrut, Roxana E., Watson, Donald A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795467/
https://ncbi.nlm.nih.gov/pubmed/26502157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b02832
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