Nuclear expression of Lyn, a Src family kinase member, is associated with poor prognosis in renal cancer patients

BACKGROUND: 8000 cases of renal cancer are diagnosed each year in the UK, with a five-year survival rate of 50 %. Treatment options are limited; a potential therapeutic target is the Src family kinases (SFKs). SFKs have roles in multiple oncogenic processes and promote metastases in solid tumours. T...

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Pubblicato in:BMC Cancer
Autori principali: Roseweir, Antonia K., Qayyum, Tahir, Lim, Zhi, Hammond, Rachel, MacDonald, Alasdair I., Fraser, Sioban, Oades, Grenville M., Aitchison, Michael, Jones, Robert J., Edwards, Joanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794832/
https://ncbi.nlm.nih.gov/pubmed/26984511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2254-9
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