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Quantitative thermophoretic study of disease-related protein aggregates

Amyloid fibrils are a hallmark of a range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. A detailed understanding of the physico-chemical properties of the different aggregated forms of proteins, and of their interactions with other compounds of diagnostic or therape...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wolff , Manuel, Mittag, Judith J., Herling, Therese W., Genst, Erwin De, Dobson, Christopher M., Knowles, Tuomas P. J., Braun, Dieter, Buell, Alexander K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794802/
https://ncbi.nlm.nih.gov/pubmed/26984748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22829
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