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Cutaneous Side Effects of BRAF Inhibitors in Advanced Melanoma: Review of the Literature
The incidence of melanoma has recently been increasing. BRAF mutations have been found in 40–60% of melanomas. The increased activity of BRAF V600E leads to the activation of downstream signaling through the mitogen-activated protein kinase (MAPK) pathway, which plays a key role as a regulator of ce...
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| 發表在: | Dermatol Res Pract |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Hindawi Publishing Corporation
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794559/ https://ncbi.nlm.nih.gov/pubmed/27042173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5361569 |
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