p73 is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network

We report that p73 is expressed in multiciliated cells (MCCs), is required for MCC differentiation, and directly regulates transcriptional modulators of multiciliogenesis. Loss of ciliary biogenesis provides a unifying mechanism for many phenotypes observed in p73 knockout mice including hydrocephal...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Marshall, Clayton B, Mays, Deborah J, Beeler, J Scott, Rosenbluth, Jennifer M, Boyd, Kelli L, Guasch, Gabriela L Santos, Shaver, Timothy M, Tang, Lucy J, Liu, Qi, Shyr, Yu, Venters, Bryan J, Magnuson, Mark A, Pietenpol, Jennifer A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794398/
https://ncbi.nlm.nih.gov/pubmed/26947080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.02.035
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