A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic residual cancer in the tumor bed could be used to decrease the risk of a positive surgical margin, reduce rates of reexcision, and tailor adjuvant therapy. We used a protea...

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Detaylı Bibliyografya
Yayımlandı:Sci Transl Med
Asıl Yazarlar: Whitley, Melodi Javid, Cardona, Diana M., Lazarides, Alexander L., Spasojevic, Ivan, Ferrer, Jorge M., Cahill, Joan, Lee, Chang-Lung, Snuderl, Matija, Blazer, Dan G., Hwang, E. Shelley, Greenup, Rachel A., Mosca, Paul J., Mito, Jeffrey K., Cuneo, Kyle C., Larrier, Nicole A., O’Reilly, Erin K., Riedel, Richard F., Eward, William C., Strasfeld, David B., Fukumura, Dai, Jain, Rakesh K., Lee, W. David, Griffith, Linda G., Bawendi, Moungi G., Kirsch, David G., Brigman, Brian E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794335/
https://ncbi.nlm.nih.gov/pubmed/26738797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad0293
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