The Impact of Myeloperoxidase and Activated Macrophages on Metaphase II Mouse Oocyte Quality

Myeloperoxidase (MPO), an abundant heme-containing enzyme present in neutrophils, monocytes, and macrophages, is produced in high levels during inflammation, and associated with poor reproductive outcomes. MPO is known to generate hypochlorous acid (HOCl), a damaging reactive oxygen species (ROS) ut...

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Pubblicato in:PLoS One
Autori principali: Shaeib, Faten, Khan, Sana N., Thakur, Mili, Kohan-Ghadr, Hamid-Reza, Drewlo, Sascha, Saed, Ghassan M., Pennathur, Subramaniam, Abu-Soud, Husam M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794194/
https://ncbi.nlm.nih.gov/pubmed/26982351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151160
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