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Temperature Sensitivity of Two-Pore (K(2P)) Potassium Channels

At normal body temperature, the two-pore potassium channels TREK-1 (K(2P)2.1/KCNK2), TREK-2 (K(2P)10.1/KCNK10), and TRAAK (K(2P)4.1/KCNK2) regulate cellular excitability by providing voltage-independent leak of potassium. Heat dramatically potentiates K(2P) channel activity and further affects excit...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Top Membr
Prif Awduron: Schneider, Eve R., Anderson, Evan O., Gracheva, Elena O., Bagriantsev, Sviatoslav N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794111/
https://ncbi.nlm.nih.gov/pubmed/25366235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-800181-3.00005-1
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