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The Impact of Cell Density and Mutations in a Model of Multidrug Resistance in Solid Tumors
In this paper we develop a mathematical framework for describing multidrug resistance in cancer. To reflect the complexity of the underlying interplay between cancer cells and the therapeutic agent, we assume that the resistance level is a continuous parameter. Our model is written as a system of in...
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| Publicado no: | Bull Math Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794109/ https://ncbi.nlm.nih.gov/pubmed/24553772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-014-9936-8 |
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