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The Role of Cell Density and Intratumoral Heterogeneity in Multidrug Resistance

Recent data have demonstrated that cancer drug resistance reflects complex biological factors including tumor heterogeneity, varying growth, differentiation, apoptosis pathways, and cell density. As a result, there is a need to find new ways to incorporate these complexities in the mathematical mode...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Lavi, Orit, Greene, James M., Levy, Doron, Gottesman, Michael M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782773/
https://ncbi.nlm.nih.gov/pubmed/24163380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1768
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