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The Role of Cell Density and Intratumoral Heterogeneity in Multidrug Resistance

Recent data have demonstrated that cancer drug resistance reflects complex biological factors including tumor heterogeneity, varying growth, differentiation, apoptosis pathways, and cell density. As a result, there is a need to find new ways to incorporate these complexities in the mathematical mode...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Lavi, Orit, Greene, James M., Levy, Doron, Gottesman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4782773/
https://ncbi.nlm.nih.gov/pubmed/24163380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1768
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