Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly apolipoprotein epsilon-4 carriers

Changes in cerebral blood flow are an essential feature of Alzheimer’s disease and have been linked to apolipoprotein E-genotype and cerebral amyloid-deposition. These factors could be interdependent or influence cerebral blood flow via different mechanisms. We examined apolipoprotein E-genotype, am...

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Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Michels, Lars, Warnock, Geoffrey, Buck, Alfred, Macauda, Gianluca, Leh, Sandra E, Kaelin, Andrea M, Riese, Florian, Meyer, Rafael, O’Gorman, Ruth, Hock, Christoph, Kollias, Spyros, Gietl, Anton F
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794091/
https://ncbi.nlm.nih.gov/pubmed/26661143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15605847
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