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Optical Antisense Tumor Targeting in Vivo with an Improved Fluorescent DNA Duplex Probe
Fluorescent conjugated DNA oligonucleotides for antisense targeting of mRNA has the potential of improving tumor/normal tissue ratios over that achievable by nuclear antisense imaging. By conjugating the Cy5.5 emitter to the 3′ equivalent end of a 25 mer phosphorothioate (PS) antisense major DNA and...
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| Publicat a: | Bioconjug Chem |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4793961/ https://ncbi.nlm.nih.gov/pubmed/19489604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9000933 |
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