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Multiple-Objective Optimal Designs for Studying the Dose Response Function and Interesting Dose Levels
We construct an optimal design to simultaneously estimate three common interesting features in a dose-finding trial with possibly different emphasis on each feature. These features are (1) the shape of the dose-response curve, (2) the median effective dose and (3) the minimum effective dose level. A...
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| Published in: | Int J Biostat |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4793387/ https://ncbi.nlm.nih.gov/pubmed/26565557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/ijb-2015-0044 |
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