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Multiple-Objective Optimal Designs for Studying the Dose Response Function and Interesting Dose Levels

We construct an optimal design to simultaneously estimate three common interesting features in a dose-finding trial with possibly different emphasis on each feature. These features are (1) the shape of the dose-response curve, (2) the median effective dose and (3) the minimum effective dose level. A...

詳細記述

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書誌詳細
出版年:Int J Biostat
主要な著者: Hyun, Seung Won, Wong, Weng Kee
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793387/
https://ncbi.nlm.nih.gov/pubmed/26565557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/ijb-2015-0044
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