Sitagliptin decreases ventricular arrhythmias by attenuated glucose-dependent insulinotropic polypeptide (GIP)-dependent resistin signalling in infarcted rats

Myocardial infarction (MI) was associated with insulin resistance, in which resistin acts as a critical mediator. We aimed to determine whether sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, can attenuate arrhythmias by regulating resistin-dependent nerve growth factor (NGF) expression in...

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Publicado en:Biosci Rep
Autores principales: Lee, Tsung-Ming, Chen, Wei-Ting, Chang, Nen-Chung
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2016
Materias:
Original Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793300/
https://ncbi.nlm.nih.gov/pubmed/26811539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150139
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