H4K44 acetylation facilitates chromatin accessibility during meiosis

Meiotic recombination hotspots are associated with histone post-translational modifications and open chromatin. However, it remains unclear how histone modifications and chromatin structure regulate meiotic recombination. Here, we identify acetylation of histone H4 at Lys44 (H4K44ac) occurring on th...

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Udgivet i:Cell Rep
Main Authors: Hu, Jialei, Donahue, Greg, Dorsey, Jean, Govin, Jérôme, Yuan, Zuofei, Garcia, Benjamin A., Shah, Parisha P., Berger, Shelley L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793274/
https://ncbi.nlm.nih.gov/pubmed/26628362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.070
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