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Histone Acetylation Regulates Chromatin Accessibility: Role of H4K16 in Inter-nucleosome Interaction

The N-terminal tail of histone H4 is an indispensable mediator for inter-nucleosome interaction, which is required for chromatin fiber condensation. H4K16 acetylation (H4K16Ac) activates gene transcription by influencing both chromatin structure and interplay with nonhistone proteins. To understand...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Zhang, Ruihan, Erler, Jochen, Langowski, Jörg
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300776/
https://ncbi.nlm.nih.gov/pubmed/27931745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.11.015
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