Tissue-Plasminogen Activator Attenuates Alzheimer's Disease-Related Pathology Development in APPswe/PS1 Mice

Alzheimer's disease (AD) is the leading cause of dementia among elderly population. AD is characterized by the accumulation of beta-amyloid (Aβ) peptides, which aggregate over time to form amyloid plaques in the brain. Reducing soluble Aβ levels and consequently amyloid plaques constitute an at...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuropsychopharmacology
Main Authors: ElAli, Ayman, Bordeleau, Maude, Thériault, Peter, Filali, Mohammed, Lampron, Antoine, Rivest, Serge
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793113/
https://ncbi.nlm.nih.gov/pubmed/26349911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.279
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