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The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects elderly persons, evolving with age to reach severe cognitive impairment. Amyloid deposits and neurofibrillary tangles constitute the main pathological hallmarks of AD. Amyloid deposits are initiated by the excessi...

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Bibliografiske detaljer
Main Authors: ElAli, Ayman, Rivest, Serge
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595512/
https://ncbi.nlm.nih.gov/pubmed/23494712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00045
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