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The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects elderly persons, evolving with age to reach severe cognitive impairment. Amyloid deposits and neurofibrillary tangles constitute the main pathological hallmarks of AD. Amyloid deposits are initiated by the excessi...

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Détails bibliographiques
Auteurs principaux: ElAli, Ayman, Rivest, Serge
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595512/
https://ncbi.nlm.nih.gov/pubmed/23494712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00045
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