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The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects elderly persons, evolving with age to reach severe cognitive impairment. Amyloid deposits and neurofibrillary tangles constitute the main pathological hallmarks of AD. Amyloid deposits are initiated by the excessi...

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Detalhes bibliográficos
Main Authors: ElAli, Ayman, Rivest, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595512/
https://ncbi.nlm.nih.gov/pubmed/23494712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00045
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