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Remote loading of doxorubicin into liposomes by transmembrane pH gradient to reduce toxicity toward H9c2 cells

The use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. Entrapped DOX in liposome has been shown to reduce cardiotoxicity. Results showed that about 92% of the total drug was encapsulated in liposome. The release experiments showed a weak DOX leakage in both culture medium and...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Saudi Pharm J
Päätekijät: Alyane, Mohamed, Barratt, Gillian, Lahouel, Mesbah
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792903/
https://ncbi.nlm.nih.gov/pubmed/27013909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2015.02.014
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