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Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities

In continuation to our previous work, thiazolopyrimidines 2a–x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine hydrobromides 1a–x using polyphosphoric acid. On the other hand, thiazolo[3,2-a]pyrimidine-3-one 3 was coupled with aryldiazonium salts or condensed...

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Библиографические подробности
Опубликовано в: :Saudi Pharm J
Главные авторы: Abdel Moty, Samia G., Hussein, Mostafa A., Abdel Aziz, Salah A., Abou-Salim, Mahrous A.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4792894/
https://ncbi.nlm.nih.gov/pubmed/27013904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2013.12.016
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